The concept for the ENDECE library of proprietary compounds is based on the premise that complex diseases involve multiple genes within specific signaling pathways and therefore;
- May be addressable via modulation of gene networks and signaling pathways.
- Ligands for nuclear receptors having similar yet unique structures activate nuclear receptors in unique manners.
- Elucidation of the gene networks and signaling pathways under control of ligands within ENDECE’s library enables the identification of novel therapeutics.
We are experts in designing and characterizing small-molecule compounds and associating their biological activities at the gene level with therapeutic targets they may impact.