NDC-1308 A MULTIPLE TARGET APPROACH FOR REMYELINATION
The myelin sheath protects and insulates the nerves in the brain and spinal cord. Myelin production is not a single target event. Multiple genes are known to be up regulated to induce oligodendrocyte progenitor cells (OPCs) to differentiate into mature oligodendrocytes that produce and maintain the myelin sheath in healthy individuals. This is a process called oligodendrogenesis.
In patients with MS, their immune and inflammatory pathways expose nerves in the brain and spinal cord by destroying their protective the myelin sheath, a process called demyelination.