About NDC-1308 For Inducing Remyelination

How the Body Makes Myelin
Oligodendrogenesis:
the body’s natural process for forming mature, myelinating oligodendrocytes leading to myelin sheaths. The process start from oligodendrocyte progenitor cells (OPCs) that are located throughout the central nervous system (CNS).

NDC-1308 Induces the Body’s Natural System for Oligodendrogenisis
Step 1:
Oligodendrocyte progenitor cells (OPCs) are present but quiescentNDC-1308
Designed to up-regulate key genes to induce remyelinationStep 2:
Gene activated by NDC-1308
Step 3:
Pre-oligodendrocytes become pre-myelinating oligodendrocytesStep 4:
Pre-myelinating oligodendrocytes become myelinating oligodendrocytesA Multiple Target Approach
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