About Multiple Sclerosis


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Multiple sclerosis (MS):

Multiple sclerosis (MS) is an unpredictable, often debilitating disease of the central nervous system (CNS) that disrupts the flow of information within the brain, and between the brain and the body.
About Muptiple Sclerosis

An Uncertain Future


Affects

More than 2 million people in the world
400,000 in the US.


MS AffectsMost people diagnosed between the ages of 20 and 50.


Cause

Although not fully understood, demyelination of axons in the CNS is caused by the immune system attacking the myelin sheath.


MS Causes

Types of MS and Progression


Relapsing Remitting (RRMS)


Most common


Characterized by clearly defined attacks of new or increasing neurological symptoms called relapses or exacerbations


Relapses can be followed by periods of partial or complete recovery (remissions)


Secondary Progressive (SPMS)

Most people who are diagnosed with RRMS will eventually transition to a secondary progressive course in which there is a progressive worsening of neurologic function (accumulation of disability) over time.


Primary Progressive (PPMS)

Worsening neurologic function (accumulation of disability) from the onset of symptoms, without early relapses or remissions.


Signs and Symptoms

Severity and specific symptoms of MS in any one person cannot yet be predicted.

MS Affects

Vision loss


MS Affects

Pain


MS Affects

Impaired cognition


MS Affects

Weakness impaired mobility

Current Therapies


Modulate the immune system to slow disease progression.


Currently there are no therapies that cause remyelination.


MS Affects

of patients diagnosed with RRMS advance to progressive MS within 19 years of diagnosis

Current Therapies

ENDECE

ENDECE has discovered a drug with the ability to induce the process for restoring and repairing the myelin sheath.

NDC 1308

NDC-1308

A new drug with the potential to induce remyelination, the process for restoring and repairing the myelin sheath in demyelinating diseases including osmotic demyelination syndrome, transverse myelitis and multiple sclerosis.

For more information go to About NDC-1308



NDC-1308

A new drug with the potential to induce remyelination in demyelinating diseases including

ODS / CPM / EPM and Multiple Sclerosis


To request more information go to; ENDECE.com/contact