ABOUT DEMYELINATING DISEASES


Conditions that result in damage to the myelin sheath in the central nervous system (CNS).

DEMYELINATING DISEASES

Demyelination may occur in one or a combination of specific areas in the CNS.

Demyelinating Diseases

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TRANSVERSE MYELITIS:

(Spinal Cord)

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MULTIPLE SCLEROSIS (MS):

(Brain and Spinal Cord)

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OPTIC NEURITIS:

(Optic Nerve)

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ODS:

(Pontine Area of the Brain)

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NEUROMYELITIS OPTICA:

(Optic Nerve and Spinal Cord)

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ACUTE DISSEMINATED ENCEPHALOMYELITIS:

(Brain and Spinal Cord)

Symptoms

Symptoms vary greatly from disease to disease and person to person and may result in;


Physical and or cognitive impairment


Chronic progressive disability over years


One time event which may improve over time

Causes

Some types of demyelinating disorders occur when your immune system attacks your own tissues. But in many cases, doctors still aren’t certain what causes these conditions.



Current Therapies

current therapiesCurrent Treatments Focus On;

  • Minimizing the effects of the attacks
  • Slowing the course of the disease
  • Managing symptoms

To date there are no approved therapies for repairing or restoring myelin.

ENDECE Approach To Remyelination

ENDECE has discovered and is developing NDC-1308, a new therapy designed to up-regulate key genes within oligodendrocyte progenitor cells (OPCs) to induce OPC differentiation into mature oligodendrocytes responsible for remyelination.


NDC-1308

A new drug with the potential to induce remyelination, the process for restoring and repairing the myelin sheath.
To learn more go to Developing NDC-1308




NDC-1308

A new drug with the potential to induce remyelination in demyelinating diseases including

ODS / CPM / EPM and Multiple Sclerosis


To request more information go to; ENDECE.com/contact